R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes.

HIV-1 is a pathogen cashel tail bag that T cell responses fail to control.HIV-1gp120 is the surface viral envelope glycoprotein that interacts with CD4 T cells and mediates entry.HIV-1gp120 has been implicated in immune dysregulatory functions that may limit anti-HIV antigen-specific T cell responses.We hypothesized that in the context of early SHI

read more

Investigating double-diffusive natural convection in a sloped dual-layered homogenous porous-fluid square cavity

Abstract This article investigates natural convection with double-diffusive properties numerically in a vertical bi-layered square enclosure.The cavity has two parts: one part is an isotropic and homogeneous porous along the deva curl arc angel wall, and an adjacent part is an aqueous fluid.Adiabatic, impermeable horizontal walls and constant and u

read more


Inside-Out Approach of Lumbar Endoscopic Unilateral Laminotomy for Bilateral Decompression: A Detailed Technical Description, Rationale and Outcomes

Although lumbar stenosis was recognized as a contraindication for endoscopic spine surgery in the past, the advancement in endoscopic system design and development of approach techniques and strategies now enabled the endoscopic spine surgeons to manage all types of lumbar stenosis safely and more effectively.A full-endoscopic lumbar technique for

read more